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Ex vivo activation of CD4(+) T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells
The fate of HIV-infected cells after reversal of proviral latency is not well characterized. Simonetti, et al. recently showed that CD4(+) T-cells containing intact proviruses can clonally expand in vivo and produce low-level infectious viremia. We hypothesized that reversal of HIV latency by activa...
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| 出版年: | PLoS Pathog |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338860/ https://ncbi.nlm.nih.gov/pubmed/28225830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006230 |
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