HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus

BACKGROUND: HIV-1 viremia that is not suppressed by combination antiretroviral therapy (ART) is generally attributed to incomplete medication adherence and/or drug resistance. We evaluated individuals referred by clinicians for nonsuppressible viremia (plasma HIV-1 RNA above 40 copies/mL) despite re...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Halvas, Elias K., Joseph, Kevin W., Brandt, Leah D., Guo, Shuang, Sobolewski, Michele D., Jacobs, Jana L., Tumiotto, Camille, Bui, John K., Cyktor, Joshua C., Keele, Brandon F., Morse, Gene D., Bale, Michael J., Shao, Wei, Kearney, Mary F., Coffin, John M., Rausch, Jason W., Wu, Xiaolin, Hughes, Stephen H., Mellors, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598056/
https://ncbi.nlm.nih.gov/pubmed/33016926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138099
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