HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus

BACKGROUND: HIV-1 viremia that is not suppressed by combination antiretroviral therapy (ART) is generally attributed to incomplete medication adherence and/or drug resistance. We evaluated individuals referred by clinicians for nonsuppressible viremia (plasma HIV-1 RNA above 40 copies/mL) despite re...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Halvas, Elias K., Joseph, Kevin W., Brandt, Leah D., Guo, Shuang, Sobolewski, Michele D., Jacobs, Jana L., Tumiotto, Camille, Bui, John K., Cyktor, Joshua C., Keele, Brandon F., Morse, Gene D., Bale, Michael J., Shao, Wei, Kearney, Mary F., Coffin, John M., Rausch, Jason W., Wu, Xiaolin, Hughes, Stephen H., Mellors, John W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Clinical Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598056/
https://ncbi.nlm.nih.gov/pubmed/33016926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138099
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