HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus

BACKGROUND: HIV-1 viremia that is not suppressed by combination antiretroviral therapy (ART) is generally attributed to incomplete medication adherence and/or drug resistance. We evaluated individuals referred by clinicians for nonsuppressible viremia (plasma HIV-1 RNA above 40 copies/mL) despite re...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Halvas, Elias K., Joseph, Kevin W., Brandt, Leah D., Guo, Shuang, Sobolewski, Michele D., Jacobs, Jana L., Tumiotto, Camille, Bui, John K., Cyktor, Joshua C., Keele, Brandon F., Morse, Gene D., Bale, Michael J., Shao, Wei, Kearney, Mary F., Coffin, John M., Rausch, Jason W., Wu, Xiaolin, Hughes, Stephen H., Mellors, John W.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2020
Sujets:
Clinical Medicine
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598056/
https://ncbi.nlm.nih.gov/pubmed/33016926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138099
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