p53 Stabilization and Accumulation Induced by Human Vaccinia-Related Kinase 1

Variations in intracellular levels of p53 regulate many cellular functions and determine tumor susceptibility. Major mechanisms modulating p53 levels include phosphorylation and interaction of p53 with specific ubiquitin ligases that promote its degradation. N-terminal phosphorylation regulates the...

Full description

Saved in:
Bibliographic Details
Main Authors: Vega, Francisco M., Sevilla, Ana, Lazo, Pedro A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC529057/
https://ncbi.nlm.nih.gov/pubmed/15542844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10366-10380.2004
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items