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p53 Downregulates Its Activating Vaccinia-Related Kinase 1, Forming a New Autoregulatory Loop

The stable accumulation of p53 is detrimental to the cell because it blocks cell growth and division. Therefore, increases in p53 levels are tightly regulated, mainly by its transcriptional target, mdm2, that downregulates p53. Elucidation of new signaling pathways requires the characterization of t...

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Detaylı Bibliyografya
Asıl Yazarlar: Valbuena, Alberto, Vega, Francisco M., Blanco, Sandra, Lazo, Pedro A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489172/
https://ncbi.nlm.nih.gov/pubmed/16782868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00069-06
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