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The C/H3 Domain of p300 Is Required to Protect VRK1 and VRK2 from their Downregulation Induced by p53
BACKGROUND: The vaccinia-related kinase 1 (VRK1) protein, an activator of p53, can be proteolytically downregulated by an indirect mechanism, which requires p53-dependent transcription. PRINCIPAL FINDINGS: In this work we have biochemically characterized the contribution of several p53 transcription...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441436/ https://ncbi.nlm.nih.gov/pubmed/18612383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002649 |
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