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p53 Stabilization and Accumulation Induced by Human Vaccinia-Related Kinase 1
Variations in intracellular levels of p53 regulate many cellular functions and determine tumor susceptibility. Major mechanisms modulating p53 levels include phosphorylation and interaction of p53 with specific ubiquitin ligases that promote its degradation. N-terminal phosphorylation regulates the...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529057/ https://ncbi.nlm.nih.gov/pubmed/15542844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10366-10380.2004 |
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