Jun NH(2)-Terminal Kinase Phosphorylation of p53 on Thr-81 Is Important for p53 Stabilization and Transcriptional Activities in Response to Stress

The p53 tumor suppressor protein plays a key role in the regulation of stress-mediated growth arrest and apoptosis. Stress-induced phosphorylation of p53 tightly regulates its stability and transcriptional activities. Mass spectrometry analysis of p53 phosphorylated in 293T cells by active Jun NH(2)...

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Hlavní autoři: Buschmann, Thomas, Potapova, Olga, Bar-Shira, Anat, Ivanov, Vladimir N., Fuchs, Serge Y., Henderson, Scott, Fried, Victor A., Minamoto, Toshinari, Alarcon-Vargas, Dania, Pincus, Matthew R., Gaarde, William A., Holbrook, Nikki J., Shiloh, Yosef, Ronai, Ze'ev
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86905/
https://ncbi.nlm.nih.gov/pubmed/11283254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2743-2754.2001
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