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E2F1 Induces Phosphorylation of p53 That Is Coincident with p53 Accumulation and Apoptosis

It has been proposed that the E2F1 transcription factor serves as a link between the Rb/E2F proliferation pathway and the p53 apoptosis pathway by inducing the expression of p19ARF, a protein that regulates p53 stability. We find that although p19ARF contributes to p53 accumulation in response to E2...

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Detalhes bibliográficos
Main Authors: Rogoff, Harry A., Pickering, Mary T., Debatis, Michelle E., Jones, Stephen, Kowalik, Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133953/
https://ncbi.nlm.nih.gov/pubmed/12101227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5308-5318.2002
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