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Vaccinia-related Kinase 1 (VRK1) Is an Upstream Nucleosomal Kinase Required for the Assembly of 53BP1 Foci in Response to Ionizing Radiation-induced DNA Damage

Cellular responses to DNA damage require the formation of protein complexes in a highly organized fashion. The complete molecular components that participate in the sequential signaling response to DNA damage remain unknown. Here we demonstrate that vaccinia-related kinase 1 (VRK1) in resting cells...

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Detalhes bibliográficos
Main Authors: Sanz-García, Marta, Monsalve, Diana M., Sevilla, Ana, Lazo, Pedro A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390650/
https://ncbi.nlm.nih.gov/pubmed/22621922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353102
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