Proteomics Identification of Nuclear Ran GTPase as an Inhibitor of Human VRK1 and VRK2 (Vaccinia-related Kinase) Activities

Human vaccinia-related kinase (VRK) 1 is a novel serine-threonine kinase that regulates several transcription factors, nuclear envelope assembly, and chromatin condensation and is also required for cell cycle progression. The regulation of this kinase family is unknown. Mass spectrometry has permitt...

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Bibliographic Details
Main Authors: Sanz-García, Marta, López-Sánchez, Inmaculada, Lazo, Pedro A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577208/
https://ncbi.nlm.nih.gov/pubmed/18617507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700586-MCP200
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