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Differential Inhibitor Sensitivity between Human Kinases VRK1 and VRK2
Human vaccinia-related kinases (VRK1 and VRK2) are atypical active Ser-Thr kinases implicated in control of cell cycle entry, apoptosis and autophagy, and affect signalling by mitogen activated protein kinases (MAPK). The specific structural differences in VRK catalytic sites make them suitable cand...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150407/ https://ncbi.nlm.nih.gov/pubmed/21829721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023235 |
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