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VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis

Regulation of cell division requires the integration of signals implicated in chromatin reorganization and coordination of its sequential changes in mitosis. Vaccinia-related kinase 1 (VRK1) and Aurora B (AURKB) are two nuclear kinases involved in different steps of cell division. We have studied wh...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Moura, David S., Campillo-Marcos, Ignacio, Vázquez-Cedeira, Marta, Lazo, Pedro A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003988/
https://ncbi.nlm.nih.gov/pubmed/29340707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2746-7
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