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VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis

Regulation of cell division requires the integration of signals implicated in chromatin reorganization and coordination of its sequential changes in mitosis. Vaccinia-related kinase 1 (VRK1) and Aurora B (AURKB) are two nuclear kinases involved in different steps of cell division. We have studied wh...

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Bibliografiske detaljer
Udgivet i:Cell Mol Life Sci
Main Authors: Moura, David S., Campillo-Marcos, Ignacio, Vázquez-Cedeira, Marta, Lazo, Pedro A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003988/
https://ncbi.nlm.nih.gov/pubmed/29340707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2746-7
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