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Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?

DNA damage causes a local distortion of chromatin that triggers the sequential processes that participate in specific DNA repair mechanisms. This initiation of the repair response requires the involvement of a protein whose activity can be regulated by histones. Kinases are candidates to regulate an...

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Bibliografske podrobnosti
izdano v:Cell Mol Life Sci
Main Authors: Campillo-Marcos, Ignacio, Lazo, Pedro A.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986855/
https://ncbi.nlm.nih.gov/pubmed/29679095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2811-2
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