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Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?
DNA damage causes a local distortion of chromatin that triggers the sequential processes that participate in specific DNA repair mechanisms. This initiation of the repair response requires the involvement of a protein whose activity can be regulated by histones. Kinases are candidates to regulate an...
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| Veröffentlicht in: | Cell Mol Life Sci |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986855/ https://ncbi.nlm.nih.gov/pubmed/29679095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2811-2 |
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