VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage

All types of DNA damage cause a local alteration and relaxation of chromatin structure. Sensing and reacting to this initial chromatin alteration is a necessary trigger for any type of DNA damage response (DDR). In this context, chromatin kinases are likely candidates to participate in detection and...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Salzano, Marcella, Sanz-García, Marta, Monsalve, Diana M, Moura, David S, Lazo, Pedro A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623420/
https://ncbi.nlm.nih.gov/pubmed/25923214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1028708
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