Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin Dependent Kinases 1 and 2

Despite advances in targeted therapy, lung cancer remains the most common cause of cancer-related mortality in the United States. Chromosomal instability is a prominent feature in lung cancer and because it rarely occurs in normal cells, it represents a potential therapeutic target. Our prior work d...

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Publicado en:Mol Cancer Ther
Autores principales: Danilov, Alexey V., Hu, Shanhu, Orr, Bernardo, Godek, Kristina, Mustachio, Lisa Maria, Sekula, David, Liu, Xi, Kawakami, Masanori, Johnson, Faye M., Compton, Duane A., Freemantle, Sarah J., Dmitrovsky, Ethan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288839/
https://ncbi.nlm.nih.gov/pubmed/27550941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0127
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