Cyclin E Transgenic Mice: Discovery Tools for Lung Cancer Biology, Therapy, and Prevention

Por Freemantle, Sarah J., Dmitrovsky, Ethan
Publicado em 2010

Retinoid Chemoprevention Trials: Cyclin D1 in the Crosshairs

Por Freemantle, Sarah J., Guo, Yongli, Dmitrovsky, Ethan
Publicado em 2009

Testicular Germ Cell Tumors: A Paradigm for the Successful Treatment of Solid Tumor Stem Cells

Por Giuliano, Caryl J., Freemantle, Sarah J., Spinella, Michael J.
Publicado em 2006

The direct p53 target gene, FLJ11259/DRAM, is a member of a novel family of transmembrane proteins

Por Kerley-Hamilton, Joanna S., Pike, Aimee M., Hutchinson, Justine A., Freemantle, Sarah J., Spinella, Michael J.
Publicado em 2007

Involvement of MicroRNAs in Lung Cancer Biology and Therapy

Por Liu, Xi, Sempere, Lorenzo F., Guo, Yongli, Korc, Murray, Kauppinen, Sakari, Freemantle, Sarah J., Dmitrovsky, Ethan
Publicado em 2011

UBE1L represses PML/RARα by targeting the PML domain for ISG15ylation

Por Shah, Sumit J., Blumen, Steven, Pitha-Rowe, Ian, Kitareewan, Sutisak, Freemantle, Sarah J., Feng, Qing, Dmitrovsky, Ethan
Publicado em 2008

Evidence for tankyrases as antineoplastic targets in lung cancer

Por Busch, Alexander M, Johnson, Kevin C, Stan, Radu V, Sanglikar, Aarti, Ahmed, Yashi, Dmitrovsky, Ethan, Freemantle, Sarah J
Publicado em 2013

High DNA Methyltransferase 3B Expression Mediates 5-aza-deoxycytidine Hypersensitivity in Testicular Germ Cell Tumors

Por Beyrouthy, Maroun J., Garner, Kristen M., Hever, Mary P., Freemantle, Sarah J., Eastman, Alan, Dmitrovsky, Ethan, Spinella, Michael J.
Publicado em 2009

Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells

Por Tomlinson Craig R, Deng Dexin, White Kristina A, Heim Kelly C, Moore Jason H, Freemantle Sarah J, Spinella Michael J
Publicado em 2007-09-01

Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells

Por Heim, Kelly C, White, Kristina A, Deng, Dexin, Tomlinson, Craig R, Moore, Jason H, Freemantle, Sarah J, Spinella, Michael J
Publicado em 2007

Effective Capture of Circulating Tumor Cells from a Transgenic Mouse Lung Cancer Model using Dendrimer Surfaces Immobilized with anti-EGFR

Por Myung, Ja Hye, Roengvoraphoj, Monic, Tam, Kevin A., Ma, Tian, Memoli, Vincent A., Dmitrovsky, Ethan, Freemantle, Sarah J., Hong, Seungpyo
Publicado no Anal Chem (2015)

UBE1L is a retinoid target that triggers PML/RARα degradation and apoptosis in acute promyelocytic leukemia

Por Kitareewan, Sutisak, Pitha-Rowe, Ian, Sekula, David, Lowrey, Christopher H., Nemeth, Michael J., Golub, Todd R., Freemantle, Sarah J., Dmitrovsky, Ethan
Publicado em 2002

Retinoic Acid Mediates Long-Paced Oscillations in Retinoid Receptor Activity: Evidence for a Potential Role for RIP140

Por Heim, Kelly C., Gamsby, Joshua J., Hever, Mary P., Freemantle, Sarah J., Loros, Jennifer J., Dunlap, Jay C., Spinella, Michael J.
Publicado em 2009

Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

Por Bee Thomas, Ewings Katherine E, Schwarz Elisabeth, Busch Alexander M, Kasper Allison C, Snow Grace E, Spinella Michael J, Dmitrovsky Ethan, Freemantle Sarah J
Publicado em 2009-10-01

Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

Por Snow, Grace E, Kasper, Allison C, Busch, Alexander M, Schwarz, Elisabeth, Ewings, Katherine E, Bee, Thomas, Spinella, Michael J, Dmitrovsky, Ethan, Freemantle, Sarah J
Publicado em 2009

Repression of exogenous gene expression by the retinoic acid target gene G0S2

Por MA, TIAN, DONG, JESSICA P., SEKULA, DAVID J., FEI, DENNIS LIANG, LAMPH, WILLIAM W., HENDERSON, MICHAEL, LU, YUN, BLUMEN, STEVEN, FREEMANTLE, SARAH J., DMITROVSKY, ETHAN
Publicado em 2013

G0S2 suppresses oncogenic transformation by repressing a Myc-regulated transcriptional program

Por Yim, Christina Y., Sekula, David J., Hever-Jardine, Mary P., Liu, Xi, Warzecha, Joshua M., Tam, Janice, Freemantle, Sarah J., Dmitrovsky, Ethan, Spinella, Michael J.
Publicado no Cancer Res (2016)

Serine/Threonine Kinase 17A Is a Novel p53 Target Gene and Modulator of Cisplatin Toxicity and Reactive Oxygen Species in Testicular Cancer Cells

Por Mao, Pingping, Hever, Mary P., Niemaszyk, Lynne M., Haghkerdar, Jessica M., Yanco, Esty G., Desai, Damayanti, Beyrouthy, Maroun J., Kerley-Hamilton, Joanna S., Freemantle, Sarah J., Spinella, Michael J.
Publicado em 2011

Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas

Por Ma, Yan, Fiering, Steven, Black, Candice, Liu, Xi, Yuan, Ziqiang, Memoli, Vincent A., Robbins, David J., Bentley, Heather A., Tsongalis, Gregory J., Demidenko, Eugene, Freemantle, Sarah J., Dmitrovsky, Ethan
Publicado em 2007

Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin Dependent Kinases 1 and 2

Por Danilov, Alexey V., Hu, Shanhu, Orr, Bernardo, Godek, Kristina, Mustachio, Lisa Maria, Sekula, David, Liu, Xi, Kawakami, Masanori, Johnson, Faye M., Compton, Duane A., Freemantle, Sarah J., Dmitrovsky, Ethan
Publicado no Mol Cancer Ther (2016)