High DNA Methyltransferase 3B Expression Mediates 5-aza-deoxycytidine Hypersensitivity in Testicular Germ Cell Tumors

Testicular germ cell tumors (TGCTs) are the most common solid tumors of 15–35 year old men. TGCT patients are frequently cured with cytotoxic cisplatin-based therapy. However, TGCT patients refractory to cisplatin-based chemotherapy have a poor prognosis, as do those having a late relapse. Pluripote...

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Autors principals: Beyrouthy, Maroun J., Garner, Kristen M., Hever, Mary P., Freemantle, Sarah J., Eastman, Alan, Dmitrovsky, Ethan, Spinella, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795063/
https://ncbi.nlm.nih.gov/pubmed/19951990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1490
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