High DNA Methyltransferase 3B Expression Mediates 5-aza-deoxycytidine Hypersensitivity in Testicular Germ Cell Tumors

Testicular germ cell tumors (TGCTs) are the most common solid tumors of 15–35 year old men. TGCT patients are frequently cured with cytotoxic cisplatin-based therapy. However, TGCT patients refractory to cisplatin-based chemotherapy have a poor prognosis, as do those having a late relapse. Pluripote...

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Bibliografiske detaljer
Main Authors: Beyrouthy, Maroun J., Garner, Kristen M., Hever, Mary P., Freemantle, Sarah J., Eastman, Alan, Dmitrovsky, Ethan, Spinella, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795063/
https://ncbi.nlm.nih.gov/pubmed/19951990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1490
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