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Modulating splicing with small molecular inhibitors of the spliceosome

Small molecule inhibitors that target components of the spliceosome have great potential as tools to probe splicing mechanism and to dissect the splicing regulatory networks in cells. These compounds also hold promise as drug leads for diseases in which splicing regulation plays a critical role, inc...

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Detalhes bibliográficos
Publicado no:Wiley Interdiscip Rev RNA
Main Authors: Effenberger, Kerstin A., Urabe, Veronica K., Jurica, Melissa S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253128/
https://ncbi.nlm.nih.gov/pubmed/27440103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1381
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