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Breaking Up the C Complex Spliceosome Shows Stable Association of Proteins with the Lariat Intron Intermediate

Spliceosome assembly requires several structural rearrangements to position the components of the catalytic core. Many of these rearrangements involve successive strengthening and weakening of different RNA∶RNA and RNA∶proteins interactions within the complex. To gain insight into the organization o...

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Détails bibliographiques
Auteurs principaux: Coltri, Patricia, Effenberger, Kerstin, Chalkley, Robert J., Burlingame, A. L., Jurica, Melissa S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079748/
https://ncbi.nlm.nih.gov/pubmed/21526149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019061
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