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Breaking Up the C Complex Spliceosome Shows Stable Association of Proteins with the Lariat Intron Intermediate

Spliceosome assembly requires several structural rearrangements to position the components of the catalytic core. Many of these rearrangements involve successive strengthening and weakening of different RNA∶RNA and RNA∶proteins interactions within the complex. To gain insight into the organization o...

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Detalhes bibliográficos
Main Authors: Coltri, Patricia, Effenberger, Kerstin, Chalkley, Robert J., Burlingame, A. L., Jurica, Melissa S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079748/
https://ncbi.nlm.nih.gov/pubmed/21526149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019061
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