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The role of exon sequences in C complex spliceosome structure

Pre-mRNA splicing is catalyzed by a large ribonucleoprotein complex called the spliceosome. Previous electron microscopy reconstruction of C complex spliceosomes arrested between the chemical two steps of splicing revealed an averaged core structure consisting of three primary domains surrounding a...

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Detalhes bibliográficos
Main Authors: Ilagan, Janine, Yuh, Patrick, Chalkley, Robert J., Burlingame, A. L., Jurica, Melissa S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783800/
https://ncbi.nlm.nih.gov/pubmed/19761775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.09.019
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