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Modulating splicing with small molecular inhibitors of the spliceosome

Small molecule inhibitors that target components of the spliceosome have great potential as tools to probe splicing mechanism and to dissect the splicing regulatory networks in cells. These compounds also hold promise as drug leads for diseases in which splicing regulation plays a critical role, inc...

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Détails bibliographiques
Publié dans:Wiley Interdiscip Rev RNA
Auteurs principaux: Effenberger, Kerstin A., Urabe, Veronica K., Jurica, Melissa S.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253128/
https://ncbi.nlm.nih.gov/pubmed/27440103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1381
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