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Modulating splicing with small molecular inhibitors of the spliceosome

Small molecule inhibitors that target components of the spliceosome have great potential as tools to probe splicing mechanism and to dissect the splicing regulatory networks in cells. These compounds also hold promise as drug leads for diseases in which splicing regulation plays a critical role, inc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Wiley Interdiscip Rev RNA
Hauptverfasser: Effenberger, Kerstin A., Urabe, Veronica K., Jurica, Melissa S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253128/
https://ncbi.nlm.nih.gov/pubmed/27440103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1381
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