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Modulating splicing with small molecular inhibitors of the spliceosome

Small molecule inhibitors that target components of the spliceosome have great potential as tools to probe splicing mechanism and to dissect the splicing regulatory networks in cells. These compounds also hold promise as drug leads for diseases in which splicing regulation plays a critical role, inc...

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Bibliografiske detaljer
Udgivet i:Wiley Interdiscip Rev RNA
Main Authors: Effenberger, Kerstin A., Urabe, Veronica K., Jurica, Melissa S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253128/
https://ncbi.nlm.nih.gov/pubmed/27440103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1381
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