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Breaking Up the C Complex Spliceosome Shows Stable Association of Proteins with the Lariat Intron Intermediate

Spliceosome assembly requires several structural rearrangements to position the components of the catalytic core. Many of these rearrangements involve successive strengthening and weakening of different RNA∶RNA and RNA∶proteins interactions within the complex. To gain insight into the organization o...

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Bibliografiske detaljer
Main Authors: Coltri, Patricia, Effenberger, Kerstin, Chalkley, Robert J., Burlingame, A. L., Jurica, Melissa S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079748/
https://ncbi.nlm.nih.gov/pubmed/21526149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019061
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