Llwytho...
Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis
Nonribosomal peptide synthetases (NRPSs) are a family of multidomain, multimodule enzymes that synthesize structurally and functionally diverse peptides, many of which are of great therapeutic or commercial value. The central chemical step of peptide synthesis is amide bond formation, which is typic...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Proc Natl Acad Sci U S A |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5224394/ https://ncbi.nlm.nih.gov/pubmed/27994138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614191114 |
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