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Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases

Modular biosynthetic machineries such as polyketide synthases (PKSs) or nonribosomal peptide synthetases (NRPSs) give rise to a vast structural diversity of bioactive metabolites indispensable in the treatment of cancer or infectious diseases. Here, we provide evidence for different evolutionary pro...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Götze, Sebastian, Arp, Johannes, Lackner, Gerald, Zhang, Shuaibing, Kries, Hajo, Klapper, Martin, García-Altares, María, Willing, Karsten, Günther, Markus, Stallforth, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472662/
https://ncbi.nlm.nih.gov/pubmed/32953002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03633d
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