Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases

Modular biosynthetic machineries such as polyketide synthases (PKSs) or nonribosomal peptide synthetases (NRPSs) give rise to a vast structural diversity of bioactive metabolites indispensable in the treatment of cancer or infectious diseases. Here, we provide evidence for different evolutionary pro...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Götze, Sebastian, Arp, Johannes, Lackner, Gerald, Zhang, Shuaibing, Kries, Hajo, Klapper, Martin, García-Altares, María, Willing, Karsten, Günther, Markus, Stallforth, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2019
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472662/
https://ncbi.nlm.nih.gov/pubmed/32953002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03633d
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