Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases

Modular biosynthetic machineries such as polyketide synthases (PKSs) or nonribosomal peptide synthetases (NRPSs) give rise to a vast structural diversity of bioactive metabolites indispensable in the treatment of cancer or infectious diseases. Here, we provide evidence for different evolutionary pro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Götze, Sebastian, Arp, Johannes, Lackner, Gerald, Zhang, Shuaibing, Kries, Hajo, Klapper, Martin, García-Altares, María, Willing, Karsten, Günther, Markus, Stallforth, Pierre
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2019
Pynciau:
Chemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472662/
https://ncbi.nlm.nih.gov/pubmed/32953002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03633d
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