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Crystallization and preliminary crystallographic analysis of the first condensation domain of viomycin synthetase

Nonribosomal peptide synthetases (NRPSs) are large multimodular enzymes that synthesize important secondary metabolites such as antibiotics. NRPSs follow a modular synthetic logic whereby each successive amino-acid monomer is added to the peptide chain by successive multi-domain modules. The condens...

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Bibliographic Details
Main Authors: Bloudoff, Kristjan, Schmeing, T. Martin
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614167/
https://ncbi.nlm.nih.gov/pubmed/23545648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113004004
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