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Crystallization and preliminary crystallographic analysis of the first condensation domain of viomycin synthetase

Nonribosomal peptide synthetases (NRPSs) are large multimodular enzymes that synthesize important secondary metabolites such as antibiotics. NRPSs follow a modular synthetic logic whereby each successive amino-acid monomer is added to the peptide chain by successive multi-domain modules. The condens...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bloudoff, Kristjan, Schmeing, T. Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614167/
https://ncbi.nlm.nih.gov/pubmed/23545648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113004004
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