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Specific disulfide cross-linking to constrict the mobile carrier domain of nonribosomal peptide synthetases
Nonribosomal peptide synthetases are large, multi-domain enzymes that produce peptide molecules with important biological activity such as antibiotic, antiviral, anti-tumor, siderophore and immunosuppressant action. The adenylation (A) domain catalyzes two reactions in the biosynthetic pathway. In t...
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| Gepubliceerd in: | Protein Eng Des Sel |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502403/ https://ncbi.nlm.nih.gov/pubmed/25713404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzv009 |
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