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Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases

Nonribosomal peptide synthetases (NRPSs) are responsible for the synthesis of a variety of bioactive natural products with clinical and economic significance. Interestingly, these large multimodular enzyme machineries incorporate nonproteinogenic D-amino acids through the use of auxiliary epimerizat...

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Bibliografski detalji
Izdano u:Chembiochem
Glavni autori: Kim, Woojoo E., Patel, Ashay, Hur, Gene H., Tufar, Peter, Wuo, Michael G., McCammon, J. Andrew, Burkart, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632073/
https://ncbi.nlm.nih.gov/pubmed/30194895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800439
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