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Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases
Adenylation (A) domains found in all nonribosomal peptide synthetase (NRPS) modules are essential catalytic components and function as gatekeepers to select amino acid building blocks during nonribosomal peptide biosynthesis. Leveraging the strict substrate recognition characteristics of these enzym...
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Publicado no: | Chem Commun (Camb) |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4795001/ https://ncbi.nlm.nih.gov/pubmed/25563804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc09412c |
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