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Structural basis for phosphopantetheinyl carrier domain interactions in the terminal module of nonribosomal peptide synthetases

Phosphopantetheine-modified carrier domains play a central role in the template-directed, biosynthesis of several classes of primary and secondary metabolites. Fatty acids, polyketides and nonribosomal peptides are constructed on multidomain enzyme assemblies using phosphopantetheinyl thioester-link...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Ye, Zheng, Tengfei, Bruner, Steven D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238681/
https://ncbi.nlm.nih.gov/pubmed/22118682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.09.018
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