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Aldehyde dehydrogenase 2 activation and coevolution of its εPKC-mediated phosphorylation sites
BACKGROUND: Mitochondrial aldehyde dehydrogenase 2 (ALDH2) is a key enzyme for the metabolism of many toxic aldehydes such as acetaldehyde, derived from alcohol drinking, and 4HNE, an oxidative stress-derived lipid peroxidation aldehyde. Post-translational enhancement of ALDH2 activity can be achiev...
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| 出版年: | J Biomed Sci |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217657/ https://ncbi.nlm.nih.gov/pubmed/28056995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0312-x |
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