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Selective phosphorylation inhibitor of δPKC-PDK protein-protein interactions; application for myocardial injury in vivo
Protein kinases regulate numerous cellular processes, including cell growth, metabolism and cell death. Because the primary sequence and the three-dimensional structure of many kinases are highly similar, the development of selective inhibitors for only one kinase is challenging. Furthermore, many p...
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Publicado no: | J Am Chem Soc |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065007/ https://ncbi.nlm.nih.gov/pubmed/27218445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b02724 |
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