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Selective phosphorylation inhibitor of δPKC-PDK protein-protein interactions; application for myocardial injury in vivo

Protein kinases regulate numerous cellular processes, including cell growth, metabolism and cell death. Because the primary sequence and the three-dimensional structure of many kinases are highly similar, the development of selective inhibitors for only one kinase is challenging. Furthermore, many p...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Qvit, Nir, Disatnik, Marie-Hélène, Sho, Jie, Mochly-Rosen, Daria
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065007/
https://ncbi.nlm.nih.gov/pubmed/27218445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b02724
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