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Engineered Substrate-Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics

Most protein kinases phosphorylate multiple substrates, each of which induces different and sometimes opposing functions. Determining the role of phosphorylation of each substrate following a specific stimulus is a challenge but is essential to elucidate the role of that substrate in the signaling e...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Qvit, Nir, Kornfeld, Opher S., Mochly-Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308906/
https://ncbi.nlm.nih.gov/pubmed/27860071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201605429
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