ロード中...

Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation

BACKGROUND: Protein disulfide isomerase (PDI) is required for thrombus formation. We previously demonstrated that glycosylated quercetin flavonoids such as isoquercetin inhibit PDI activity and thrombus formation in animal models, but whether extracellular PDI represents a viable anticoagulant targe...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Stopa, Jack D., Neuberg, Donna, Puligandla, Maneka, Furie, Bruce, Flaumenhaft, Robert, Zwicker, Jeffrey I.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214567/
https://ncbi.nlm.nih.gov/pubmed/28097231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89373
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!