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Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo
Protein disulfide isomerase (PDI) catalyzes the oxidation reduction and isomerization of disulfide bonds. We have previously identified an important role for extracellular PDI during thrombus formation in vivo. Here, we show that endothelial cells are a critical cellular source of secreted PDI, impo...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society of Hematology
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996122/ https://ncbi.nlm.nih.gov/pubmed/20668226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278184 |
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