Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

Protein disulfide isomerase (PDI) catalyzes the oxidation reduction and isomerization of disulfide bonds. We have previously identified an important role for extracellular PDI during thrombus formation in vivo. Here, we show that endothelial cells are a critical cellular source of secreted PDI, impo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jasuja, Reema, Furie, Bruce, Furie, Barbara C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2010
Gaiak:
Thrombosis and Hemostasis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996122/
https://ncbi.nlm.nih.gov/pubmed/20668226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278184
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