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Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

Protein disulfide isomerase (PDI) catalyzes the oxidation reduction and isomerization of disulfide bonds. We have previously identified an important role for extracellular PDI during thrombus formation in vivo. Here, we show that endothelial cells are a critical cellular source of secreted PDI, impo...

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主要な著者: Jasuja, Reema, Furie, Bruce, Furie, Barbara C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996122/
https://ncbi.nlm.nih.gov/pubmed/20668226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278184
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