Platelets are required for enhanced activation of the endothelium and fibrinogen in a mouse thrombosis model of APS

Antiphospholipid syndrome (APS) is defined by thrombosis, fetal loss, and the presence of antiphospholipid antibodies, including anti–β2-glycoprotein-1 autoantibodies (anti-β2GP1) that have a direct role in the pathogenesis of thrombosis in vivo. The cellular targets of the anti-β2GP1 autoantibody/β...

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Bibliographic Details
Main Authors: Proulle, Valerie, Furie, Richard A., Merrill-Skoloff, Glenn, Furie, Barbara C., Furie, Bruce
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2014
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110663/
https://ncbi.nlm.nih.gov/pubmed/24825863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554980
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