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Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins
Extracellular protein disulfide isomerase (PDI) is required for platelet thrombus formation and fibrin generation after arteriolar wall injury in live mice. PDI is secreted from platelets and endothelial cells on cellular activation, but the mechanism of capture of secreted PDI within the injured va...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401216/ https://ncbi.nlm.nih.gov/pubmed/22653978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-372532 |
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