Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice

Protein disulfide isomerase (PDI) derived from intravascular cells is required for thrombus formation. However, it remains unclear whether platelet PDI contributes to the process. Using platelet-specific PDI–deficient mice, we demonstrate that PDI-null platelets have defects in aggregation and adeno...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kim, Kyungho, Hahm, Eunsil, Li, Jing, Holbrook, Lisa-Marie, Sasikumar, Parvathy, Stanley, Ronald G., Ushio-Fukai, Masuko, Gibbins, Jonathan M., Cho, Jaehyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Thrombosis and Hemostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739031/
https://ncbi.nlm.nih.gov/pubmed/23788140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492504
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge