Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice

Protein disulfide isomerase (PDI) derived from intravascular cells is required for thrombus formation. However, it remains unclear whether platelet PDI contributes to the process. Using platelet-specific PDI–deficient mice, we demonstrate that PDI-null platelets have defects in aggregation and adeno...

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Bibliografski detalji
Glavni autori: Kim, Kyungho, Hahm, Eunsil, Li, Jing, Holbrook, Lisa-Marie, Sasikumar, Parvathy, Stanley, Ronald G., Ushio-Fukai, Masuko, Gibbins, Jonathan M., Cho, Jaehyung
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2013
Teme:
Thrombosis and Hemostasis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739031/
https://ncbi.nlm.nih.gov/pubmed/23788140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492504
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