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Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice

Protein disulfide isomerase (PDI) derived from intravascular cells is required for thrombus formation. However, it remains unclear whether platelet PDI contributes to the process. Using platelet-specific PDI–deficient mice, we demonstrate that PDI-null platelets have defects in aggregation and adeno...

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Main Authors: Kim, Kyungho, Hahm, Eunsil, Li, Jing, Holbrook, Lisa-Marie, Sasikumar, Parvathy, Stanley, Ronald G., Ushio-Fukai, Masuko, Gibbins, Jonathan M., Cho, Jaehyung
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739031/
https://ncbi.nlm.nih.gov/pubmed/23788140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-03-492504
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