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Extracellular protein disulfide isomerase regulates ligand-binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammation

β2 integrins play a crucial role during neutrophil recruitment into the site of vascular inflammation. However, it remains unknown how ligand-binding activity of the integrin is regulated. Using fluorescence intravital microscopy in mice generated by crossing protein disulfide isomerase (PDI) floxed...

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Bibliografische gegevens
Hoofdauteurs: Hahm, Eunsil, Li, Jing, Kim, Kyungho, Huh, Sungjin, Rogelj, Snezna, Cho, Jaehyung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650702/
https://ncbi.nlm.nih.gov/pubmed/23460613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-467985
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