A critical role for extracellular protein disulfide isomerase during thrombus formation in mice

Thiol isomerases, including protein disulfide isomerase (PDI), catalyze disulfide oxidation, reduction, and isomerization, thereby playing an important role in protein synthesis. To determine whether extracellular PDI mediates thrombus formation in an animal model, PDI expression, platelet accumulat...

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Hauptverfasser: Cho, Jaehyung, Furie, Barbara C., Coughlin, Shaun R., Furie, Bruce
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248441/
https://ncbi.nlm.nih.gov/pubmed/18292814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34134
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