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Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of β3 integrins

Extracellular protein disulfide isomerase (PDI) is required for platelet thrombus formation and fibrin generation after arteriolar wall injury in live mice. PDI is secreted from platelets and endothelial cells on cellular activation, but the mechanism of capture of secreted PDI within the injured va...

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Bibliografiske detaljer
Main Authors: Cho, Jaehyung, Kennedy, Daniel R., Lin, Lin, Huang, Mingdong, Merrill-Skoloff, Glenn, Furie, Barbara C., Furie, Bruce
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401216/
https://ncbi.nlm.nih.gov/pubmed/22653978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-372532
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