Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination

Glioblastoma is the most lethal brain tumor and harbors glioma stem cells (GSCs) with potent tumorigenic capacity. The function of GSCs in tumor propagation is maintained by several core transcriptional regulators including c-Myc. c-Myc protein is tightly regulated by posttranslational modification....

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Fang, Xiaoguang, Zhou, Wenchao, Wu, Qiulian, Huang, Zhi, Shi, Yu, Yang, Kailin, Chen, Cong, Xie, Qi, Mack, Stephen C., Wang, Xiuxing, Carcaboso, Angel M., Sloan, Andrew E., Ouyang, Gaoliang, McLendon, Roger E., Bian, Xiu-wu, Rich, Jeremy N., Bao, Shideng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2017
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206492/
https://ncbi.nlm.nih.gov/pubmed/27923907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151673
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller