The Zinc Finger Transcription Factor ZFX is Required for Maintaining the Tumorigenic Potential of Glioblastoma Stem Cells

Glioblastomas are highly lethal brain tumors containing tumor-propagating glioma stem cells (GSCs). The molecular mechanisms underlying the maintenance of the GSC phenotype are not fully defined. Here we demonstrate that the zinc finger and X-linked transcription factor (ZFX) maintains GSC self-rene...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cells
Prif Awduron: Fang, Xiaoguang, Huang, Zhi, Zhou, Wenchao, Wu, Qiulian, Sloan, Andrew E., Ouyang, Gaoliang, Mclendon, Roger E., Yu, Jennifer S., Rich, Jeremy N., Bao, Shideng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349564/
https://ncbi.nlm.nih.gov/pubmed/24831540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1730
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