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Endothelin-1–Rho kinase interactions impair lung structure and cause pulmonary hypertension after bleomycin exposure in neonatal rat pups

Bronchopulmonary dysplasia (BPD) is the chronic lung disease associated with premature birth, characterized by impaired vascular and alveolar growth. In neonatal rats bleomycin decreases lung growth and causes pulmonary hypertension (PH), which is poorly responsive to nitric oxide. In the developing...

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Podrobná bibliografie
Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Gien, Jason, Tseng, Nancy, Seedorf, Gregory, Kuhn, Katherine, Abman, Steven H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206397/
https://ncbi.nlm.nih.gov/pubmed/27760762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00066.2016
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